Phytochemicals: nutrient-gene interactions
نویسندگان
چکیده
منابع مشابه
Gene-nutrient interactions and DNA methylation.
Many micronutrients and vitamins are critical for DNA synthesis/repair and maintenance of DNA methylation patterns. Folate has been most extensively investigated in this regard because of its unique function as methyl donor for nucleotide synthesis and biological methylation. Cell culture and animal and human studies showed that deficiency of folate induces disruption of DNA as well as alterati...
متن کاملGenetics of obesity: gene x nutrient interactions.
Obesity results from a long-term positive energy balance, in which gene-related differences may account for some of the disparities found in weight gain among populations. However, the rising prevalence of obesity in developed and developing societies must reflect lifestyle changes. Despite that the genetic background remains stable over many generations, obesity may be derived from a failure o...
متن کاملWorkshop Report Nutrient–gene interactions in benefit–risk analysis
John Hesketh*, Iwona Wybranska, Yvonne Dommels, Maria King, Ruan Elliott, Catalina Pico and Jaap Keijer Institute of Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne, UK Collegium Medicum, Jagiellonian University, Krakow, Poland RIKILT – Institute of Food Safety, Wageningen, The Netherlands Institute of Food Research, Norwich, UK University of the Balearic Islands, P...
متن کاملA transgenic mouse model for gene-nutrient interactions.
Diets or nutritional supplements contain many nutrients and other components that may interact, which adds a layer of complexity to their evaluation. A well-controlled experimental model that can eliminate or minimize the confounding factors of diet is critical for addressing nutrient-gene interactions. The newly generated fat-1 transgenic mouse was genetically engineered to carry a gene, namel...
متن کاملNutrient-gene interactions determine mitochondrial function: effect of dietary fat.
The effect on mitochondrial respiration of feeding hydrogenated coconut oil, corn oil, or menhaden oil (MO) to diabetes-prone BHE/cdb rats and normal Sprague Dawley (SD) rats was studied. Both fat source and strain affected the temperature dependence of succinate-supported respiration. The transition temperature was greater in BHE/cdb rats than in the SD rats. The efficiency of ATP synthesis as...
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ژورنال
عنوان ژورنال: Revista Brasileira de Ciências Farmacêuticas
سال: 2007
ISSN: 1516-9332
DOI: 10.1590/s1516-93322007000400023